THE TOXICITY OF BROMADIOLONE TO THE MALAYSIAN WOOD RAT RATTUS TIOMANICUS

LEE, C.H. AND MASTOR. T.

SUMMARY

Oral intubation and no-choice feeding tests were conducted to determine the toxicity and efficacy of trromadiolone against R. tiomanicus trapped from cocoa-coconut fields in Hilir Perak. The single dose oral LD 50 is 2.27 (1.89-2.67) mg/kg while the mean lethal feeding period LFP 50 is 1.29 (0.79-1.68) days. The mean duration to death was five to seven days with the shortest being two days and the longest was eleven days. No acute poisoning svmptoms were seen indicating that bait shyness would not be induced. The variability in susceptibility of the rats to the poison showst he possibility of selectiont for resistant rats after the poison has been in use for a long time. As such the LD 95 and the LFp 95 within the upper 95% fiducial limits can be used as a baseline to monitor/detect resistance. The anticoagulant nature of the poison renders it safe for use. With good bait acceptance, the advantage of a single dose effect and the short duration to death, bromadiolone is an effective rodenticide for the control of R. tiomanicus and would be an addition to the current convenrional rodenticides.

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